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Gallbladder problems right upper abdominal pain, particularly after eating fatty foods Severe allergic reactions rash, swelling of face or throat, difficulty breathing Diabetic retinopathy complications sudden vision changes (in patients with pre-existing retinopathy) Acute kidney injury particularly in the context of severe dehydration The MHRA advises that patients should be counselled about these risks before starting treatment

Do not use if you are allergic to hydroxocobalamin, cyanocobalamin, cobalt, or any ingredients in this product (can cause severe allergic reaction)